Accidental Intrathecal Injection of Aminophylline in Spinal Anesthesia

Accidental intrathecal injection of aminophylline in spinal anesthesia.

M EDICATION error has been an unfortunate chapter in the history of spinal anesthesia since its invention in 1899. Many catastrophic incidents have occurred from intrathecal injection of local anesthetics contaminated with other chemicals as well as the use of drugs not intended or approved for intrathecal administration. In such situations, patient outcomes depend on the nature of the contamin...

Accidental Intrathecal Injection of Tranexamic Acid

Tranexamic acid (TXA) is a popular antifibrinolytic drug that is commonly used in patients with bleeding disorder. Major morbidities and mortalities have been reported following inadvertent intrathecal injection of TXA. In this paper, inadvertent intrathecal injection of TXA has resulted from similarities in appearance between TXA and heavy bupivacaine 0.5% ampoules. The patient experienced sev...

Midazolam in Spinal Anesthesia — Intrathecal or Intravenous?

Accidental intrathecal injection of dopamine hydrochloride resulting in analgesic effects

provided the original work is properly cited. CC Medication errors are defined as any error in the delivery process, whether there are any adverse consequences or not [1]. In the present case report, we describe an accidental intrathecal injection of dopamine hydrochloride (DA) which has not been previously reported in human. We were blinded to the fact due to the analgesic and anesthetic effec...

Intrathecal Injection of Amitriptyline and Doxepin for Spinal Anesthesia in Animal Studies

I read with a great interest the recent article by Alebouyeh et al. about intrathecal administration of amitriptyline and doxepin to induce spinal blockade and comparison of their effects with those of bupivacaine (1). Alebouyeh et al. reported that intrathecal injection of various drugs with different mechanisms is an intriguing issue in anesthesiology and pain management. Antidepressants are ...